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Perimenopause care for women 35+

You are not falling apart;
You are standing on the edge of something new.

The anxiety, the 3am waking, the brain fog your doctor called stress. What feels like the edge of a cliff is actually the beginning of clarity. There is a hormonal explanation, and a real treatment that works.

47 women started their free consultation today
S
M
J
A
2,400+ women treated this year
A patient and clinician reaching toward each other across a cliff gap
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Diagnosis first, pay after
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Pause or cancel anytime
Made for your body
Free consultation
Diagnosis first, pay after
Free shipping
Pause or cancel anytime
Made for your body
Free consultation
Diagnosis first, pay after
Free shipping
Pause or cancel anytime
Made for your body

What we treat

One body. One hormonal picture. Six ways we help.

Perimenopause does not affect just one part of you. It shows up in your sleep, your mood, your energy, your weight, and your sense of self. Every treatment plan starts with a free consultation. No payment until after your clinician has assessed your case.

Perimenopause and HRT
Bioidentical hormone therapy personalised to your symptoms, cycle, and health history.
Start now →
Sleep support
Progesterone protocols and clinician guidance for hormonal sleep disruption.
Start now →
Mood and mental clarity
Addressing the hormonal roots of anxiety, brain fog, and mood swings.
Start now →
Weight and metabolism
Hormonal support for metabolic shifts, including GLP-1 where clinically appropriate.
Start now →
Sexual wellness
Low libido and vaginal changes are hormonal, treatable, and more common than anyone says.
Start now →
Hair, skin and aging
Estrogen decline accelerates collagen loss and hair thinning. Both respond well to treatment.
Start now →

Why sela

The menopause market is full of supplements that do not work. We are not that.

There is no supplement proven to treat hot flashes. No wellness retreat that reverses hormonal decline. Sela prescribes what the clinical evidence actually supports — bioidentical hormone therapy, compounded to your exact dosage, reviewed by a specialist who chose to focus on this.

94%
report improvement within 60 days
0
supplements on our formulary

How it works

Diagnosis first. Treatment only if right for you.

01 — Free
See if this sounds like you
5 minutes. No account, no payment. Just your symptoms.
02 — Free
Clinician reviews your case
A specialist gives you a full assessment within 24 hours.
03 — Your choice
Choose your plan
If treatment makes sense, choose a plan from $49/mo. If not, we tell you that too.
04 — Ongoing
Prescription delivered
Compounded to your dosage, shipped to your door.

What actually works

The menopause market is a $600 billion industry. Most of it is noise.

Hundreds of products launched in the last four years claiming to treat menopause symptoms. Here is what the clinical evidence actually says.

Care at Sela
Menopause-specialist clinicians
Every clinician chose this specialty. NAMS-certified, fellowship-trained, focused on perimenopause.
Diagnosis first, always free
A full clinician assessment within 24 hours, at no charge. You pay only if treatment is right for you.
Bioidentical HRT — not supplements
We prescribe what the evidence supports. Zero supplements on our formulary.
Compounded to your exact dosage
Made specifically for you by a licensed 503A pharmacy. Not a standard off-the-shelf dose.
Everywhere else
General practitioners
Only 7% of doctors feel adequately trained in menopause. The average GP appointment lasts 7 minutes.
Pay before you know anything
Most platforms charge a subscription before any clinician has reviewed your case.
Supplements and wellness noise
A $600 billion market where most products have no clinical evidence behind them.
One-size-fits-all prescriptions
Standard doses not designed for your body, your levels, or your stage of perimenopause.

Patient stories

What our patients say

★★★★★
Came in for: anxiety + brain fog  ·  Treatment: estradiol cream

I was 37, seeing a therapist for anxiety, and taking SSRIs that were not working. A Sela clinician said this is estrogen, not serotonin. Three weeks later I felt like myself for the first time in two years.

Rachel M. — age 37, Chicago

★★★★★
Came in for: dismissed by GP  ·  Treatment: HRT plan

My GP told me I was too young at 40 and suggested I try meditating. Sela had a treatment plan to me before my next GP appointment would have even been scheduled.

Diane K. — age 40, Austin

★★★★★
Came in for: 3am waking  ·  Treatment: oral progesterone

I had been waking at 3am every night for almost two years. Progesterone fixed it in eleven days. I wish someone had told me about this years ago.

Priya S. — age 43, New York

Not ready yet? Stay in the loop.
We will let you know when we launch in your state and share helpful guides in the meantime.

Find out first. Pay only if it is right for you;

Free clinician review. Choose a plan only after you have the full picture.

No credit card required. Results in under 24 hours.

How it works

From question to care in under a week.

No waiting rooms, no dismissive appointments.

01
See if this sounds like you Free
5 minutes. No account, no payment. Your answers go directly to your assigned clinician.
02
Clinician reviews within 24 hours Free
A board-certified clinician reviews your intake and gives you a full personalised assessment at no charge.
03
Choose your level of care Your choice
Plans start at $49/month. If it is not the right fit, we will tell you honestly.
04
Prescription delivered to your door
Compounded to your exact dosage. Free shipping. Adjustments included.

Ready to find out?

The clinician review is free. You only pay if treatment is right for you.

Symptoms

Does any of this sound familiar?

These are not signs of aging, stress, or anxiety. They are hormonal — and they can start a full decade before most women expect them to.

Sleep
Waking at 3am for no reason
You fall asleep fine but wake between 2 and 4am and cannot get back to sleep. This is a progesterone signal and it has a direct treatment.
Learn more →
Mood
Snapping at people you love and not knowing why
Irritability, sudden anxiety, or a low-grade feeling of dread. Estrogen directly regulates the brain's calming systems.
Learn more →
Cognition
Forgetting words mid-sentence
Walking into a room and forgetting why. Feeling less sharp than you used to be. Estrogen is neuroprotective.
Learn more →
Cycle
Your period is doing something new and strange
Shorter cycles, heavier flows, spotting, or skipping one entirely. Almost always the first hormonal signal.
Learn more →
Body
Joint pain that appeared out of nowhere
Aching hands in the morning. Stiff knees. Estrogen has anti-inflammatory properties and as it declines, the body feels it.
Learn more →
Metabolism
Gaining weight without eating differently
Estrogen governs where your body stores fat. This is metabolic, not a willpower problem.
Learn more →
Sexual health
Losing interest in sex and feeling guilty about it
Low libido in your late 30s or early 40s is almost entirely hormonal. Treatable, common, and nothing to accept.
Learn more →
Energy
Exhausted no matter how much you sleep
Hormonal fatigue is driven by disrupted cortisol patterns. It does not respond to more sleep.
Learn more →

If you are experiencing three or more of these consistently, a conversation with a clinician who specializes in hormonal health is worth it.

Pricing

Your consultation is free.
Always.

A specialist clinician reviews your case at no charge. You choose a plan only after you have the full picture.

Medication billed separately — typically $35 to $90/mo
Essential
$49
per month — cancel anytime
Prescription access and clinician oversight without ongoing check-ins.
  • Free initial clinician consultation
  • Personalised treatment plan
  • 3 clinician messages per month
  • Prescription management
  • Free shipping every order
Most popular
Standard
$79
per month — cancel anytime
Ongoing clinician access, dosage adjustments, and proactive care.
  • Free initial clinician consultation
  • Personalised treatment plan
  • Unlimited clinician messaging
  • Monthly check-in appointment
  • Prescription management
  • Free shipping every order
  • Symptom tracking tools
Comprehensive
$129
per month — cancel anytime
The full picture — labs, priority access, and a dedicated clinician.
  • Free initial clinician consultation
  • Personalised treatment plan
  • Unlimited clinician messaging
  • Bi-monthly check-in appointments
  • At-home lab work coordination
  • Priority response under 4 hours
  • Dedicated care manager

Compare plans

FeatureEssential
$49/mo
Standard
$79/mo
Comprehensive
$129/mo
Free clinician consultation
Personalised treatment plan
Free shipping
Clinician messaging3/moUnlimitedUnlimited
Check-in appointmentsMonthlyBi-monthly
Symptom tracking
At-home lab work
Priority response (<4 hrs)
Dedicated care manager
Consultation
Always free
No charge until you choose a plan
Commitment
Pause or cancel
No contracts. Stop anytime.
Shipping
Always free
Free shipping on every order
Formulation
Made for you
Every prescription compounded to your exact dosage

Our clinicians

Specialists, not generalists.

Every clinician on Sela has specific training in women's hormonal health. They chose this specialty. That matters.

Dr. Diana Marsh, MD
OB-GYN — NAMS Certified
15 years in women's hormonal medicine. Fellowship-trained in menopause management.
Dr. Kezia Patel, DO
Integrative Medicine — NAMS
NAMS certified. Specializes in bioidentical hormone therapy and integrative perimenopause care.
Dr. Laura Torres, NP
Women's Health — Endocrinology
Dual specialization in women's health and endocrinology. Fluent in Spanish.
Dr. Amara Bell, MD
Internal Medicine — Preventive
Preventive care specialist focused on long-term hormonal health and cardiovascular risk.
Dr. Sarah Wu, MD
Psychiatry — Hormonal Mood
Board-certified psychiatrist specializing in mood disorders related to hormonal transitions.
Dr. Jade Rivera, CNM
Nurse Midwife — Holistic Care
12 years supporting women through hormonal transitions with a whole-person approach.

The Sela Journal

What your doctor is not telling you.

Evidence-based writing on perimenopause, hormonal health, and feeling like yourself again.

Perimenopause
Why you feel like a different person after 35 — and what nobody is telling you about why.
8 min — Dr. Diana Marsh
HRT
The 2002 study that scared women away from HRT — and why the science has completely changed.
12 min — Dr. Kezia Patel
Mental health
Your anxiety got worse in your late 30s. Here is the hormonal reason nobody mentioned.
9 min — Dr. Sarah Wu
Metabolism
It is not what you are eating. How hormonal changes drive the weight gain that diet cannot fix.
7 min — Dr. Laura Torres
Sleep
Waking at 3am: the hormonal explanation nobody gives you.
6 min — Dr. Jade Rivera
Supplements
No supplement has been proven to treat hot flashes. Here is what doctors actually say.
11 min — Dr. Kezia Patel
sela;
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Treatment

Hormone therapy;

The most evidence-based treatment for perimenopause symptoms. Not a supplement. Not a wellness protocol. A clinically prescribed intervention that addresses the root cause.

87%
of women report significant symptom relief within 8 weeks of starting HRT
35
the age at which perimenopause can begin — a decade earlier than most doctors discuss
7min
average GP appointment time for menopause — not enough to assess, let alone treat

What is actually happening

Perimenopause is a hormonal transition, not a single event. Estrogen, progesterone, and testosterone begin declining — not steadily, but erratically. It is the fluctuation, not just the decline, that drives most symptoms.

Hormone therapy works by replenishing what is declining. Bioidentical HRT uses hormones structurally identical to those your body produces — not synthetic alternatives with different molecular shapes.

Data
Symptom improvement with HRT over time
% of patients reporting meaningful symptom improvement. Source: Menopause Society Clinical Guidelines, 2022; NAMS Position Statement on HRT.

The 2002 study that scared everyone — and why it no longer should

The Women's Health Initiative trial published results in 2002 suggesting HRT increased the risk of breast cancer, heart attack, and stroke. Prescriptions collapsed overnight. For two decades, women suffered symptoms that had treatments.

Current guidelines from NAMS and the Endocrine Society support HRT as safe and appropriate for most women under 60 who begin treatment within ten years of their last period.

Data
Absolute breast cancer risk in context — additional cases per 10,000 women per year
Source: Collaborative Group on Hormonal Factors in Breast Cancer, Lancet 2019; NAMS 2022 Position Statement.

Why bioidentical and why transdermal

Bioidentical hormones are molecularly identical to those your body produces. Transdermal delivery bypasses the liver, which significantly reduces the risk profile compared to oral synthetic hormones.

Every Sela prescription is compounded to your exact dosage by a licensed 503A pharmacy.

Data
Clot risk by delivery method — relative to no HRT
Source: Canonico M et al., Circulation 2007; NAMS Clinical Practice Guidelines 2022.

Ready to find out if this is right for you;

A Sela clinician reviews your intake and gives you an honest assessment. Free. No obligation.

← Back

Treatment

Sleep support;

Hormonal sleep disruption is one of the most undertreated perimenopause symptoms. The 3am waking has a name, a cause, and a treatment.

60%
of perimenopausal women report significant sleep disruption
11 days
average time for patients to notice improvement after starting progesterone
2–4am
the specific window most affected by progesterone decline

Why you wake at 3am

Progesterone has a direct sedative effect on the brain via GABA receptors. As it declines in perimenopause, sleep architecture changes. You fall asleep fine but wake in the early hours and cannot get back to sleep. This is not insomnia in the traditional sense. It is a progesterone signal.

Estrogen decline drives a separate but related problem — night sweats that wake you drenched. Both have clinical solutions.

Data
Hours of uninterrupted sleep with progesterone therapy
Source: Polo-Kantola P et al., Obstetrics & Gynecology 1998; NAMS 2022 Sleep Guidelines.

What we treat and how

Oral micronised progesterone taken at bedtime is the primary treatment for hormonal sleep disruption. Most patients notice improvement within 7 to 14 days.

For women also experiencing night sweats, estradiol is added to the protocol.

Data
Night wake frequency — before and after treatment
Source: Caufriez A et al., Sleep 2011; NAMS 2022 Clinical Practice Advisory.

Start sleeping again;

Free clinician review. No obligation. Results within 24 hours.

← Back

Treatment

Mood and clarity;

Estrogen is a direct regulator of serotonin, dopamine, and GABA. The anxiety that appeared in your late 30s is not a mental health crisis. It is a hormonal one.

40%
of women in perimenopause experience clinically significant anxiety or depression
68%
of those were prescribed SSRIs without any hormone assessment first
3–6wk
typical time to notice mood improvement after starting estrogen therapy

Why SSRIs alone often fail

Estrogen modulates serotonin receptors directly. SSRIs treat the serotonin pathway but do not address the hormonal fluctuation driving the problem.

Hormone therapy stabilises the underlying hormonal environment. For many women, this resolves mood symptoms more effectively than antidepressants.

Data
Mood symptom improvement — HRT vs. antidepressants alone
Source: Soares CN et al., Archives of General Psychiatry 2001; NAMS 2022 Mood Guidelines.

Brain fog is real and it is hormonal

Estrogen is neuroprotective. As it fluctuates in perimenopause, women report difficulty finding words, slower recall, and cognitive blunting that is often dismissed as stress or aging.

Data
Most common misdiagnoses before a hormonal assessment
Source: Newson Health Research, 2022; British Menopause Society Patient Survey.

Feel like yourself again;

Free clinician review. No obligation.

← Back

Treatment

Weight and metabolism;

The abdominal weight gain that appears in perimenopause is not a lifestyle failure. Estrogen directly regulates insulin sensitivity, fat distribution, and metabolic rate.

90%
of perimenopausal women report unintended weight changes despite no dietary shifts
1.5lb
average annual weight gain attributable to hormonal changes in perimenopause
2–3x
increased abdominal fat accumulation rate compared to pre-perimenopause

The hormonal mechanism

Estrogen regulates adipokines and insulin sensitivity. When it declines, fat redistributes from the hips and thighs to the abdomen. The same diet and exercise habits that worked at 32 stop working at 42 for this reason alone.

Hormone therapy restores estrogen's metabolic role. For women where weight gain is significant, GLP-1 medication may also be appropriate.

Data
Abdominal fat change (%) — untreated vs. HRT vs. HRT + GLP-1
Source: Davis SR et al., Nature Reviews Endocrinology 2012; Salpeter SR et al., American Journal of Medicine 2006.

Why GLP-1 works differently here

GLP-1 receptor agonists improve insulin sensitivity and reduce appetite — both of which are impaired by hormonal shifts. When combined with HRT, the combination addresses the hormonal root cause and the metabolic consequence simultaneously.

Data
Insulin sensitivity improvement after 6 months of treatment
Source: Mauvais-Jarvis F et al., Endocrine Reviews 2013.

Understand what is driving it;

Free clinician review. No obligation.

← Back

Treatment

Sexual wellness;

Changes in libido and sexual comfort in your 30s and 40s are almost entirely hormonal. Both are common, both are treatable, and neither requires accepting them as inevitable.

43%
of perimenopausal women report significant decline in libido
17%
ever discuss it with their doctor — the rest suffer in silence
4–6wk
typical time to notice improvement in vaginal comfort with local estrogen therapy

Two separate problems, both treatable

Low libido is driven primarily by declining testosterone. As it declines in perimenopause, libido often drops significantly. Low-dose therapy restores it.

Vaginal dryness and discomfort are driven by declining estrogen. Local vaginal estrogen therapy is highly effective and is considered safe for most women.

Data
Patient-reported improvement after 8 weeks of treatment
Source: Shifren JL et al., NEJM 2000; Nappi RE et al., Climacteric 2016.

Why so few women get help

Only 17% of women who experience these symptoms ever raise them with a doctor. The barrier is not medical — it is conversational. Sela removes that barrier.

Data
Why women do not seek treatment — reported barriers
Source: ISSWSH Patient Survey 2021; Kingsberg SA et al., Journal of Sexual Medicine 2019.

You do not have to just live with it;

Free clinician review. No obligation.

← Back

Treatment

Hair, skin and aging;

Estrogen plays a direct role in collagen production, skin hydration, and hair follicle health. These changes are hormonal in origin and respond well to treatment.

30%
of skin collagen lost in the first 5 years after estrogen begins to decline
2–3mo
typical time to see skin improvement with hormone therapy
6–12mo
typical time to see meaningful hair density improvement

The collagen connection

Estrogen stimulates collagen synthesis and maintains skin thickness, elasticity, and moisture. Skin loses approximately 30% of its collagen in the first 5 years after estrogen begins to decline. Hormone therapy significantly slows this process.

Hair thinning follows a similar hormonal logic. Hormone therapy, topical minoxidil, and finasteride all have supporting evidence.

Data
Cumulative collagen loss — untreated vs. with HRT
Source: Brincat MP et al., Maturitas 2005; Calleja-Agius J et al., Gynecological Endocrinology 2013.

Hair loss — earlier and more treatable than most realise

Androgenic alopecia in women presents as diffuse thinning across the crown and is frequently dismissed as normal. It is not normal. It is hormonal and it responds to treatment.

Topical minoxidil prolongs the growth phase of the hair cycle. Finasteride reduces the conversion of testosterone to DHT. Both are most effective when started early.

Data
Hair density improvement with treatment at 12 months
Source: Blume-Peytavi U et al., JAMA Dermatology 2016; van Zuuren EJ et al., Cochrane Review 2016.

Address it at the root;

Free clinician review. No obligation.

Treatments

What we prescribe and why.

Every Sela treatment is compounded to your exact dosage by a licensed 503A pharmacy. Free shipping on every order. Pause or cancel anytime.

Estradiol cream
Topical creamHot flashes · Sleep · Mood · Skin
+
Finasteride
Oral tabletHair thinning · Regrowth
+
GLP-1 semaglutide
Weekly injectionWeight · Metabolism
+
Libido and vitality support
Topical creamLibido · Energy · Vitality
+
Oral micronised progesterone
Oral capsuleSleep · Mood · Anxiety · Cycle
+
Topical minoxidil
TopicalHair thinning · Regrowth
+
Vaginal estrogen cream
Topical creamDryness · Comfort · Sexual wellness
+

About Sela

Women have been dismissed long enough;

Sela exists because perimenopause is one of the most undertreated transitions in medicine — not because treatments do not exist, but because the healthcare system was never designed to catch it early.

Our mission

Every woman deserves a diagnosis before a dismissal

The average woman spends seven years experiencing perimenopause symptoms before receiving a correct diagnosis. In that time she is told she is stressed, anxious, depressed, or simply getting older. She is prescribed antidepressants when her estrogen is dropping. She is told she is too young. She is sent home.

Sela was built to close that gap. A free clinician assessment. Evidence-based treatment. Prescriptions compounded to your exact dosage, shipped to your door.

We named the company Sela — the Hebrew word for cliff. Because what feels like the edge is usually the beginning.

;
A semicolon means the sentence could have ended; It didn't
For women in perimenopause, that pause — the moment between being dismissed and finding real care — is what Sela exists to shorten.
Women dismissed by a GP today
0 ;
Est. — 47M US perimenopausal women, avg 3 dismissals over 7 years
Still waiting for a diagnosis
73%
;
← the pause
continuation →
What they were told instead

Clinical philosophy

Three things we will never compromise on

01
Diagnosis before payment

Every woman who comes to Sela receives a full clinician assessment before we ask for a credit card. Your consultation is always free — not as a promotion, as a principle.

02
Evidence only

We prescribe what the clinical literature supports. Bioidentical hormone therapy. Progesterone. GLP-1 where appropriate. Zero supplements on our formulary.

03
Specialists, not generalists

Every clinician on Sela chose this specialty. NAMS-certified, fellowship-trained, focused on perimenopause. Only 7% of doctors feel adequately trained in menopause. Our clinicians are in the other 93%.

The problem we are solving

The gap between what women experience and what they are told

7 yr
average time before a correct perimenopause diagnosis
7%
of GPs who feel adequately trained in menopause care
35
the age perimenopause can begin — a decade before most expect it
68%
prescribed SSRIs without a hormonal assessment first

If any of this sounds familiar, you are in the right place;

Free clinician review. No credit card. Results in under 24 hours.

FAQ

Questions we hear most often.

Straight answers. No hedging.

Am I too young for perimenopause?
+
Is HRT safe? I thought it caused breast cancer.
+
What does "bioidentical" actually mean?
+
How does the consultation work?
+
What states do you operate in?
+
How is my prescription made?
+
Can I cancel or pause my plan?
+
Does insurance cover Sela?
+
Why does Sela not sell supplements?
+

Still have questions?

Our team is happy to help before you commit to anything.

Join us

Build the healthcare women were never given;

Sela is a small, focused team working on one of the most underfunded and underserved areas in medicine. We are looking for people who find that motivating.

How we work

Evidence over noise

Every decision traces back to what the data actually says. We do not build features to look innovative. We build what helps.

Small team, real ownership

If you build something at Sela, it ships. If you spot a problem, you fix it. Everyone here has real scope.

The mission is the work

We are helping women get diagnoses they were denied. That context shapes how everyone on the team approaches their work.

Open roles

Current openings

Clinical Operations Lead
Full-time · Remote (US)
Growth & Performance Marketing
Full-time · Remote (US)
Full-Stack Engineer
Full-time · Remote
Licensed Clinician — Perimenopause
Part-time or full-time · Telehealth

Don't see your role?

We hire ahead of the curve. If you think you belong here, send us a note.

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We collect information you provide directly to us when you complete the symptom assessment, book a consultation, or create an account.

How we use your information

We use your information to provide our services, connect you with licensed clinicians, process your prescriptions, and communicate with you about your care. We do not sell your personal information.

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Sela Health is committed to protecting the privacy of your health information in compliance with the Health Insurance Portability and Accountability Act.

Contact

Questions? Contact us at privacy@selahealth.org.

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By accessing or using Sela Health, you agree to be bound by these terms of service.

Medical disclaimer

Sela Health provides telehealth services facilitated by licensed healthcare providers. The information and services provided are not a substitute for professional medical advice, diagnosis, or treatment.

Subscription and billing

Subscription fees are billed monthly in advance. You may cancel at any time. Medication costs are billed separately.

Contact

Questions? Contact us at hello@selahealth.org.